There are more than 30,000 of us working hard to prevent, treat, cure and stop some of the most devastating and complex diseases of our time. From heart disease and HIV to Alzheimer’s and cancer, we are mobilizing on issues that touch everyone’s lives. Our mission is to transform people’s lives and fundamentally change the way diseases are managed, interpreted and prevented. We believe that the best way to change things is to challenge them. So every day, in more than 150 countries, we bring together cutting-edge science and the most creative minds in the industry to approach disease in a different way. We seek not only to innovate, but to provide people with the tools to make informed decisions and achieve the best possible health outcomes. We are developing treatments for patients in six major therapeutic areas:

• • Cardiovascular and metabolic disease
• • Immunology
• • Infectious diseases and vaccines
• • Neuroscience
• • Oncology
• • Pulmonary hypertension